Visceral larva migrans

Visceral larva migrans is a condition in humans caused by the migratory larvae of certain nematodes, humans being a terminal host, and was first reported in 1952.^[1] Nematodes causing such zoonotic infections are Baylisascaris procyonis,^[2] Toxocara canis,^[3] Toxocara cati,^[3] and Ascaris suum.^[4] These nematodes can infect but not mature in humans and after migrating through the intestinal wall, travel with the blood stream to various organs where they cause inflammation and damage. Affected organs can include the liver, heart (causing myocarditis) and the CNS (causing dysfunction, seizures, and coma). A special variant is ocular larva migrans where usually T. canis larvae travel to the eye.

Cutaneous larva migrans is a condition where nematodes such as Ancylostoma braziliense migrate to the skin.

A list of causative agents of larva migrans syndromes is not agreed upon and varies with the author.^[5]

See also

• Toxocariasis

References

1. ^ Beaver, P. C.; Snyder, C. H.; Carrera, G. M.; Dent, J. H.; Lafferty, J. W. (1952). "Chronic eosinophilia due to visceral larva migrans; report of three cases". Pediatrics 9 (1): 7–19. PMID 14911260.  edit
2. ^ Gavin, P. J.; Kazacos, K. R.; Shulman, S. T. (2005). "Baylisascariasis". Clinical Microbiology Reviews 18 (4): 703. doi:10.1128/CMR.18.4.703-718.2005. PMC 1265913. PMID 16223954. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1265913.  edit
3. ^ ^{a b} Beaver, PC (1959). "Visceral and cutaneous larva migrans". Public health reports 74 (4): 328–32. PMC 1929226. PMID 13645880. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1929226.  edit
4. ^ Sakai, S.; Shida, Y.; Takahashi, N.; Yabuuchi, H.; Soeda, H.; Okafuji, T.; Hatakenaka, M.; Honda, H. (2006). "Pulmonary Lesions Associated with Visceral Larva Migrans Due to Ascaris suum or Toxocara canis: Imaging of Six Cases". American Journal of Roentgenology 186 (6): 1697–1702. doi:10.2214/AJR.04.1507. PMID 16714661.  edit
5. ^ Iowa State University (May, 2005). "Larva migrans". http://www.cfsph.iastate.edu/Factsheets/pdfs/larva_migrans.pdf. Retrieved November 10,2010.